المشاريع الممولة خارجيا

Simulating Genetic Toggle Switch Using RLC Electrical Circuit

  • د. احمد منصور العمري
  • جامعة اليرموك
  • 3000

Project Objectives:

Simulating the genetic toggle switch using RLC circuit helps to understand the mechanism of biological circuits and solving ODEs using hardware solvers instead of software solvers and with further research we might able to replace the work of faulty genes or a faulty protein properly by a hardware device that increase or decrease the amount of a gene expression.
 

Milestones and expected result:

Proposing a hardware simulation for the genetic toggle switch network. We should show that there is a possibility to simulate genetic networks using RLC circuit that helps to understand the mechanism of biological circuits and solving ODEs using hardware solvers instead of software solvers and with further research we might able to replace the work of faulty genes or a faulty protein properly by a hardware device that increase or decrease the amount of a gene expression
The major challenge in achieving this simulation is represented by the difficulty of building an appropriate circuit that simulates the response of the solved ODEs. The idea promises for much complicated circuits such as the biological clock of Neurospora Crassa or electrical circuit ODE solver.